How AISDR runs autonomous SDR agents at scale with AgentMail

Company: AISDR, an AI SDR agent that finds in-market buyers using real-time signals and books meetings

Problem: Programmatic inbox provisioning at scale, without a human in the loop

Result: ~500 AgentMail inboxes in production, sending ~7,000 emails per week

Stack: AgentMail + AISDR

What AISDR Is

AISDR is an AI SDR agent that focuses on lead quality over volume. It finds people across the web in real time using buying signals, researches each prospect, and reaches out across email and LinkedIn with messages that read like a real rep wrote them. Replies are qualified by the agent, and meetings get booked when prospects are ready to talk.

The deliberate, research-first approach is how AISDR differentiates from AI outreach tools optimized for volume. Their public messaging is direct about it: outbound fails the moment relevance becomes optional.

The Problem

For an AI SDR operating at scale, the email infrastructure has to handle two things. Outbound at volume that stays deliverable. And inbound threading so prospect replies route to the right conversation and the agent can respond in-thread.

The central constraint for AISDR was inbox provisioning. They needed automatic inbox creation without a human in the loop.

Why AgentMail

AISDR went with AgentMail because the platform covered every feature their flow needed. Programmatic inboxes, send and receive, webhooks for real-time inbound, IMAP and SMTP.

"AgentMail is a YC company. It has simple documentation with all needed features for our flow."

Dmytro Omelian, AISDR

AISDR started on the basic tier and upgraded the following month after hitting the limit faster than expected.

"Support was great. We started with basic tier and moved to the next tier next month since we hit the limit faster than expected (which is good) :)"

Dmytro Omelian, AISDR